这个靶向构建在第35位(位置103,CAGTGA)插入了TGA终止密码子。通过Cre介导的重组,去除了含突变的外显子上游的含有人类β-actin启动子、ΔTK1和Neo cassette的内含子。(来源:J:316365)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac
Targeted
Insertion, Nucleotide substitutions
--
1
26
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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