Tg(Neurog1-cre/ERT2)G1CTahi

The transgene was constructed using a genomic BAC clone RP24-347K19 encoding the mouse neurogenin (Neurog)1 gene by replacing the entire coding sequence in exon1 with a CreERT2 cassette and the loxP site in the vector backbone (pTARBAC) was deleted by replacement with the zeocin resistance gene. The eleven mouse lines that independently received the transgene integration were then assayed for the Cre recombinase activities. Through this screen, one line (G1C) was selected by the highest recombination rate. (J:306016)