CRISPR/Cas9技术在第3外显子上游插入了loxP位点和含FRT标签的诺卡因抗性基因,同时在第4外显子下游也放置了另一个loxP位点。通过Flp介导的重组,选择性载体被去除,导致第3-4外显子区域被标记为可剪接。(来源:J:305579)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Endonuclease-mediated
插入
--
1
3
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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