CRISPR对启动子和外显子1的靶向处理产生了无功能等位基因。 Western blot结果显示背根神经节中没有蛋白质表达(来源:J:305107)
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CRISPR-targeting of the promoter and exon 1 produced a null allele. Western blot analysis confirmed the absence of protein expression in dorsal root ganglia. (J:305107)