CRISPR技术引入的框架移位在exon 2产生了一个早发的终止密码子,这导致了睾丸中蛋白的缺失。 Western blot分析证实了这一点(来源:J:305434)
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CRISPR-targeting introduced a frame shift in exon 2 that produced a premature stop codon. Western blot analysis confirmed the absence of protein in the testis. (J:305434)