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中文
3'端的第三个外显子(Exon 3)通过CRISPR/Cas9技术用sgRNA(靶向AGGCCGCATACTGATGAAAGAGGT，包含了剪接起始点)进行了修饰，导致了36个碱基的缺失，包括了外显子和内含子序列以及Exon 3的剪接起始点。RT-PCR实验表明，由于缺失了剪接点，这个位点在mRNA的剪接过程中被跳过了。免疫荧光实验也确认了这个等位基因上肽表达的缺失。(来源：J:285572)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
