在小鼠Fgf15基因的第三外显子,在终止密码子之前插入了T2A-cre-T2A-tdTomato基因座,通过胚胎干细胞的同源重组实现。随后,通过与表达Flp重组酶的 mice杂交,删除了位于终止密码子3'末端的FRT-flanked PGK-neomycin cassette。(来源:J:305713)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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