CRISPR/Cas9基因编辑技术被用来在编码序列的第696位核苷酸后插入一个FAH表位标签。这对应于编码蛋白质的Val232和Glu233之间的位置,外源FAH标签被插入在聚丙烯肽段预测的切割位点之后。(来源:J:300752)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x DBA/2)F1
Endonuclease-mediated
插入
--
1
1
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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