Exon 1周围有loxP位点,之后通过Cre介导的重组手段删除了。通过 Western blot 实验确认了这种等位基因在肺、脾、胸腺和阑尾淋巴结中没有肽的表达。(来源:J:238172)
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Exon 1 was flanked by loxP sites and deleted through subsequent cre-mediated recombination. Lack of peptide expression from this allele in lung, spleen, thymus and mesenteric lymph nodes was confirmed by Western blot experiments. (J:238172)