设计的质粒含有一种指导RNA(CGAGGCATAAAGGCCCTGTA),其目的是插入一种名为P2A的病毒性2A自我切割肽,该肽能促进核糖体跳过,随后紧跟一个位于内源性终止密码子上游的人类白喉毒素受体(DTR)。(来源:J:309477)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCr
Endonuclease-mediated
插入
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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