使用CRISPR/Cas9技术,针对这个重复区域设计了几条gRNA,产生了大约6个基因组的删除。这个等位基因表示的是从KRAB型锌指蛋白997基因的3'端到(包括)Vmn2r-ps103假基因的区域的删除。(引用:J:282526)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Applicable
Endonuclease-mediated
Intergenic deletion, Intragenic deletion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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