CRISPR/Cas9技术通过单引物RNAAAGGCGTAGAATGCGTTCAA,产生了一个8个碱基的缺失(CCTTTGAA),在第5外显子导致了一个移位和蛋白质下游6个氨基酸的终止。(来源:J:300837)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(FVB/N x C57BL/6J)F1
Endonuclease-mediated
基因内删除
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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