Exon 2通过CRISPR/Cas9技术用两个sgRNAs(针对CAGCAACGGGCGGTGCATCC和CGTCACACTGCCAGGCGCCC)进行靶向,产生了11个碱基的缺失(在forward strand上为ATCCCGGGCGC [GCGCCCGGGAT])。 (来源:J:300132)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count