Log In|Sign Up
中文
在19号外显子通过CRISPR/Cas9技术引入了一个与人类的K1270T等同的K1259T(由AAA变为ACC)的错义突变。下游位置增加了一个用于基因分型的silent EcoRV剪切位点突变，同时在K1270T突变两侧额外插入了两个无声的插入突变，以阻止修复后等位基因的Cas9活性。(来源：J:320991)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
