这种基因的序列是:2A自剪切肽、Cre-ERT2融合基因和一个由loxP序列 flank的诺卡因抗性基因插件,它们被直接插入在终止密码子之前。之后通过Cre介导的重组,可以去掉诺卡因抗性基因插件。这个等位基因表达的是内源肽和插入的Cre-ERT2融合肽。参考文献:J:247209, J:292580。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
--
1
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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