2A自我剪切肽的序列被插入在了diphtheria毒素受体(HBEGF/DTR)的cDNA和一个loxP位点介导的诺卡因抗性基因元件之前,这些元素紧接在终止密码子之后。后续通过Cre介导的重组会去除neo cassette,这个等位基因表达的是内源肽和插入的DTR肽。(来源:J:292580)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
--
1
3
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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