这项转基因包含了反义肌红蛋白,它使用了心脏特异性的肌球蛋白重链(MHC)启动子,只针对心脏肌肉,而不影响骨骼肌肉。实验产生了4号和10号线。4号线的心肌中肌红蛋白浓度是野生型(WT)Mb浓度的0.58倍,而10号线则是0.38倍的WT浓度。(来源:J:94077)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Applicable
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
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Year
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