这个等位基因是通过在反义链exon1中插入一个包含兔β-球蛋白polyA位点、EGFP和反向lox71/lox66变异体的条件性倒位(COIN) cassette产生的。它在功能上接近野生型,但通过Cre介导的重组会生成一个通过增强绿色荧光蛋白(EGFP)表达可检测到的缺失等位基因。(来源:J:188991)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NJ
Endonuclease-mediated
插入
--
1
--
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部