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Exon 1通过sgRNA(靶向TGAAACCAGCAAGAAGAACG)和ssODN模板进行编辑，模板中在lysine 53的密码子位置插入了一个A到T的突变，导致了提前终止翻译(p.K53*)。这是CRISPR/Cas9技术的应用。(来源：J:301313)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
