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中文
目标位点包含一个由两个FRT和两个LoxP座环绕的PGK-neo cassette，位于要切除区域的两端。要删除的区域包括了第一个外显子及其上游区域。通过与通用剔除者Cre小鼠杂交，成功去除了第一个外显子和PGK-neo cassette。 Western blot结果显示，新生纯合突变小鼠大脑匀浆中无蛋白表达。（来源：J:272122）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
