在第六外显子上游插入了一个带有5' loxP位点的FRT引导的诺姆霉素抗性基因座,而在第十二外显子下游则插入了一个带有3' loxP位点的FRT引导的PGK基因同源重组元件。通过Flp介导的重组,这些选择性基因座被去除,导致6号到12号外显子成为可翻转的。(来源:J:299741)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
插入
--
1
4
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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