Col4a4^m1H

The ENU-induced mutation was isolated in a screen looking for mice exhibiting end stage renal disease and was identified as a G to T change at position 1198 resulting in a glycine change to a stop codon at amino acid 400 (p.G400*). Immunofluorescence of kidneys confirmed absence of protein in glomeruli of homozygous mice. (J:285510)