将一个含有frt-flanked诺卡因选择标记 cassette 和位于19号染色体10261203位点,上游于exon 8的loxP序列的靶向载体插入。在生殖细胞中,通过FLP介导的重组移除了诺卡因选择标记 cassette,留下exon 9周围的loxP序列。(来源:J:244431)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
插入
--
1
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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