The KOMP targeting vector PG00082_Z_3_D01 was used to create an allele with an FRT site, lacZ gene, loxP site, neo cassette, FRT site, and loxP site upstream of exon 9 and a loxP site downstream of exon 11. Cre mediated recombination removed exons 9 11 and the neo cassette. Analysis of mRNA in testes from homozygous mice indicated absence of expression. (J:284740)