CRISPR/Cas9介导的重组在启动子下游产生了一个116bp的缺失。 Western blot分析显示,纯合小鼠中几乎检测不到蛋白质水平。(来源:J:290992)
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CRISPR/Cas9-mediated recombination created a 116 bp deletion just downstream from the start site. Western blot analysis found nearly undetectable levels of protein in homozygous mice. (J:290992)