Tg(Ar*C556G,-EGFP)NCWhw

This transgene includes a 167 kb genomic mouse Ar gene and approximately 40 kb each of 5' and 3' flanking sequence. An IRES, EGFP reporter gene, and poly A site are present after the stop codon for Ar to coexpress AR and EGFP. There is a one base pair mutation in exon 2 resulting in a C556G amino acid change in the mouse AR protein. (J:310653)