Tg(Ar*,-EGFP)CWhw

This transgene includes a 167 kb genomic mouse Ar gene and approximately 40 kb each of 5' and 3' flanking sequence. An IRES, EGFP reoporter gene, and poly A site are present after the stop codon for Ar to co-express AR and EGFP. There is a deletion of 45 base pairs in exon 1 of the mouse androgen receptor gene resulting in the deletion of 15 amino acids (363-377). (J:310653)