基于注射的定向转导(PITT)技术,使用Gt(ROSA)26Sortm1Maoh,将CFP报告基因替换成由小鼠驱动的Podocyte特异性表达的EGFP报告基因。通过Flp介导的重组,去除了诺卡因抗性基因元件。lox2272序列仍位于上游的启动子之前。(来源:J:253434)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count