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中文
在exon 7的AGA密码子被替换为histidine( CAT)的密码子，即R318H，这在人类的ectrodactyly, ectodermal dysplasia, clefting syndrome中等同于R279H突变。此外，插入了neomycin cassette，它被loxP位点前后标记，位于exon 5上游，exon 7下游。通过Cre介导的重组，去除了neomycin cassette以及编码DNA结合区域的exons 5到7，产生了无功能的等位基因。(来源：J:294158)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
