这个转基因靶向的位点包含了puro插件、CAG启动子、floxed终止子、FRT附着的终止子、来自耐盐细菌纳塔诺玛斯pharaonis的halorhodopsin,经过N端信号肽和C端内质网出口序列的融合,与增强黄色荧光蛋白(eNpHR3-EYFP)成一个框内连接,以及木鼠肝炎病毒的后转录调控元件(WPRE,以提升mRNA的稳定性)。(来源:J:293482)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S6/SvEvTac
Targeted
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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