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中文
CRISPR/Cas9技术被用来在第3和4外显子周围添加loxP位点，并在第4外显子下游、第二个loxP位点上游插入了含FRT标签的诺卡因选择性载体。通过Cre介导的重组，去除了3和4外显子以及诺卡因载体，导致了框架突变。 Western blotting确认了中枢神经系统组织和坐骨神经中无蛋白质表达。(来源：J:295996)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
