Log In|Sign Up
中文
在CRISPR/Cas9技术中，1974位的Arginine被一个gRNA( CATTCGGGCATCCAGATCTG)和供体寡核苷酸靶向。这导致了Arginine变为Alanine的突变(p.R1974A)，从而阻止了Notch细胞内域(NICDs)的二聚化。(来源：J:296947)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
