这个靶向构建插入了位于腺病毒(Adenovirus)的剪接接受体位点,包含P1噬菌体的LoxP序列、 HSV tk 链接素启动子(HSV tk promoter)、大肠杆菌抗氨苄青霉素基因(E. coli neomycin resistance gene)、HSV tkpolyA尾巴、Aequorea victoria的mVenus编码DNA、小鼠p27K-(突变p27)基因的cDNA,以及SV40病毒的PolyA信号。(来源:J:300785)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x 129S6/SvEvTac)F1
Targeted
插入
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--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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