通过重组酶介导的 cassette 交换,利用了 loxed cassette 基因型(LCA),将编码序列替换为融合了 Cre/ERT2 的形式。随后,Flp介导的重组去除了带有 FRT 标记的 hygromycin 框架。(来源:J:296396)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
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1
3
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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