RMCE插入到了a lox71/66位点,这个带有FRT引导的hygromycin抗性元件,YFP报告基因带有SV40的polyadenylation序列,双向的四环素诱导promoter,包含Pdx1序列,再有SV40的polyA序列,以及lox2272位点。通过Flp介导的重组,选择性元件被去除了。(来源:J:296396)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S6/SvEvTac
Targeted
插入
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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