RMCE插入到了a lox71/66位点,这个带有FRT引导的hygromycin抗性元件,YFP报告基因带有SV40的polyadenylation序列,双向的四环素诱导promoter,包含Pdx1序列,再有SV40的polyA序列,以及lox2272位点。通过Flp介导的重组,选择性元件被去除了。(来源:J:296396)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count