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中文
设计了一条导向RNA( CGAGAAGGTGGACCTGATCANGG)，目标是插入导致第379位氨基酸由谷氨酰胺变为组氨酸的错义突变( Q379H)。这个突变类似于人类ESR1基因中的Q375H变异，与雌激素不敏感综合症(EIS)关联。另外，还加入了四个无声的bp改变，以防止重定向和误定向。(来源：J:295332)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
