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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Nf1
tm1Luo
Alias:
Nf1
23aIN
Nf1
23aINneo
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基础信息
表型特征
文献报道
5'剪接位点(5' SS)和与exon 23a相关的poly嘧啶重复序列被修改,以促进最终转录本中的插入。在exon 23a之后的内含子中插入了诺卡因 cassette,而在exon 23a上游则插入了第二个loxP位点。(来源:J:249893)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
6469615
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Insertion, Nucleotide substitutions
--
1
24
2
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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