Prcd^{tm1.1(KOMP)Mbp}

The insertion of the L1L2_Bact_P cassette created a deletion of size 2793 starting at position 116547922 and ending at position 116550715 of Chromosome 11 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon 1-4. The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Cre-mediated recombination removed the selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:293626)