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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Zbp1
em1Tdk
Alias:
Zbp1
deltaZalpha2
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基础信息
表型特征
文献报道
CRISPR/Cas9基因编辑技术被用来产生Zaplha2蛋白编码区域的基因序列缺失。在氨基酸序列上,这通过连接76和151位点的残基,以及删除77到150位的残基,导致了编码蛋白的Zalpha2区域的缺失。(来源:J:295921)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
6466718
C57BL/6J
Endonuclease-mediated
基因内删除
--
1
--
2
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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