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中文
在exon 4的上游插入了loxP位点，接着插入了带有FRT标签的诺卡因选择性元件和另一个loxP位点在exon 4的下游。通过Flp介导的重组移除了选择性元件，而由Cre介导的生殖细胞内exon 4的删除导致了其功能丧失。exon 4的缺失产生了一个框移，进而破坏了锌依赖的金属酶域及其下游序列。(来源：J:295274)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
