CRISPR/cas9通过重组产生了3号外显子2个碱基(TC)的缺失,导致了框架移位和早停密码子,这在转录本中被免疫组化分析证实没有蛋白质表达。(来源:J:291131)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6D2F1
Endonuclease-mediated
基因内删除
--
1
2
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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