Thap12^em1(IMPC)J

This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTTTGTTAATGTTCTATTAG and CCTTGTATATTTTCTTAAAA, which resulted in a 3412 bp deletion beginning at Chromosome 7 position 98714706 bp and ending after 98718117 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000265800 (exon 5) and 331 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 118 and early truncation 2 amino acids later. (J:188991)