在8号染色体的2号和3号内含子通过LoxP位点插入,使用了长链单链脱氧核糖核酸(lsODNs)和CRISPR/Cas9技术的sgRNAs。插入位置分别位于8:88125028-88125029和8:88125950-88125951(基于GRCm38构建)。(来源:J:282373)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count