在8号染色体的2号和3号内含子通过LoxP位点插入,使用了长链单链脱氧核糖核酸(lsODNs)和CRISPR/Cas9技术的sgRNAs。插入位置分别位于8:88125028-88125029和8:88125950-88125951(基于GRCm38构建)。(来源:J:282373)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Endonuclease-mediated
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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