Exon 4被替换为:一个loxP位点、一段来自E330037C1Rik的含有4-19号外显子的不完整cDNA、FRT序列包裹的抗氨苄青霉素基因座、第二个loxP位点、4号外显子的剪接接受体、EGFP报告基因,以及一个终止子。随后通过flp介导的重组移除了neo cassette,形成一个条件性可操作的报告基因等位基因。(来源:J:294342)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
插入
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1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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