CRISPR对exon 3的39个碱基删除,导致框移和提前终止。 Western blot结果显示胰腺中没有pritein蛋白表达。(来源:J:294035)
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CRISPR-targeting of exon 3 deleted 43 bp resulting in a frame shift and premature termination. Western blot analysis confirmed the absence of pritein expression in the pancreas. (J:294035)