BAC RP23-240p23中,基因序列(包括外显子和内含子)被修改后的rtTA2序列替换,该序列具有较低的背景活性、对多西环素更高的敏感性,并针对真核细胞进行了适应性改变。这使得tetacycline反式激活器的表达受小鼠肾素启动子的控制。(来源:J:263308)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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