这个靶向载体被设计成在Ndrg1基因起始密码子位置,以其相反的转录方向插入Cre/ERT2 cassette、polyA尾和loxP引导的PGK-Neo cassette,目标是打断第一个exon,从而消除Ndrg1的表达(来源:J:261876)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Targeted
插入
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1
3
11

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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