在Avpr1a基因的最后一个编码外显子3'末端,通过同源重组插入了IRES-mnCre:GFP(内部起始序列-IRES,Myc标签和核定位信号,连接到Cre重组酶,后接绿色荧光蛋白,再是SV40的polyadenylation序列)。这个 cassette 是通过与广泛表达Flp重组酶的动物进行杂交来用诺卡因 cassette 消除的。(来源:J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NCrl)F1
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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