使用了EuMMCR特异性导向的载体PG00141_Z_1_G10来通过同源重组产生突变小鼠。载体插入了5'端的frt-lacZ-loxP-neomycin选择基因座和3'端的loxP-frt,其中在exon 5的位置各插入了一个loxP标记。(来源:J:273065)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
STOCK 129/Sv and C57BL/6J and SJL
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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