使用了EuMMCR特异性导向的载体PG00141_Z_1_G10来通过同源重组产生突变小鼠。载体插入了5'端的frt-lacZ-loxP-neomycin选择基因座和3'端的loxP-frt,其中在exon 5的位置各插入了一个loxP标记。(来源:J:273065)
Basic Information
STOCK 129/Sv and C57BL/6J and SJL
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count