A loxP-Stop-FRT-reverse neo-FRT-loxP-CMV promoter-Rab7 cDNA cassette was introduced to intron 1 of the mouse Gt(ROSA)26Sor gene. The Rab7 cDNA is full-length and derived from mouse. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:285615)